Paolo Ciccarese, PhD

Research and Development Semantic Web Applications in Neuromedicine MIND Informatics, Mass General Institute for Neurodegenerative Disease, Neurology Department, Massachusetts General Hospital, Boston, USA
Founder and Consultant Knowledge management, workflow technologies and clinical guidelines computerization Medicognos SA, Belgium

Personal Data:

Date of birth ~ October 1973
Place of birth ~ Chiavenna, Sondrio, Italy
Citizenship ~ Italian
Current Residency ~ Boston, USA

Appointments:

2008 ~ Assistant in Neurology,
Neurology Department, Massachusetts General Hospital, Boston, USA.
2007 ~ Faculty - Instructor,
Harvard Medical School, Harvard University, Boston, USA.
2006 - 2007 ~ Research Fellow in Neurology,
Neurology Department, Massachusetts General Hospital, Boston, USA.
2006 - 2007 ~ Research Fellow in Neurology,
Harvard Medical School, Harvard University, Boston, USA.
2006 - 2007 ~ Research Fellow in Medical Informatics,
Laboratory for Medical Informatics, University of Pavia, Pavia, Italy

Education

2006 ~ PhD in Bioengineering and Bioinformatics
University of Pavia, Italy, discussing the thesis:
The Guide Project: A Clinical Knowledge Management Framework.
2002 ~ State exam for the qualification to the profession of Computer Science Engineer
2001 ~ Computer Science and Engineering Master Degree
University of Pavia, Italy, discussing the thesis:
A tool for Clinical Practice Guidelines formalization (Score: 110 out of 110).
1992 ~ Diploma from Istituto Tecnico Commerciale
Chiavenna, Sondrio, Italy (Score: 60 out of 60).

Advanced Formation:

2008 ~ Intensive Course on Biomedical Ontologies (by Professor Barry Smith).
2007 ~ Training Course in Logic for Biomedical Research (Organized by Professor Barry Smith).
2004 ~ GRID Computing: Foundamentals, tools e applications. Health Grid Working Group.
2003 ~ Data Warehousing Fundamentals. Oracle Italy.
2003 ~ Data Warehouse Database Design. Oracle Italy.
2002 ~ Object-Oriented Analysis and Design Using UML. Sun Microsystem Italy.

Professional Activities:

2008 ~ Medicognos SA, Belgium. Knowledge Architecture Consultant.
2006 ~ Policlinico S. Matteo, Pavia, Italy. Analysis, design and implementation of the Italian network for amyloidosis.
2005 ~ Medilogix PgmbH, Belgium. Analysis and Design of the architecture of a process based distributed electronic patient record.
2005 ~ Medicognos SA, Belgium. Analysis and design of a medical knowledge and workflow management framework with integrated DSS for quality, safety and disease management applications.
2005 ~ Arteram, Pavia, Italy. Developement of the website.
2004 ~ Palestra Verdelinea, Pavia, Italy. Developement of the website.
2003 ~ Sergio Elia, Vendite e Finanziamenti Immobiliari, Miano, Italy- Design and developement of a client-server information and reporting system.
2001 - 2002 ~ Consorzio di Bioingegneria e Informatica Pavese, Pavia, Italy. Consultant for clinical decision support systems.
2000 ~ MAIDS (Motorcycle Accidents in Depth Study) EUProject. Consultant for design and development of the software for data exchange between data entry tools and statistical analysis tools.

Academic Teaching Assistance at the University of Pavia, Department of Computer Engineering and Systems Science:

2005-2007 ~ Informatics: Object Oriented Analysis
2004-2007 ~ Informatics: Java Fundamentals.
2003-2007 ~ Artificial Intelligence in Medicine: Clinical Guidelines representation and dissemination
2002-2005 ~ Medical Informatics: eXtended Markup Language

Scientific Research Interests:

Knowledge Management Methods and Tools
Social Network Analysis
Clinical Practice Guideline Computerization
Business Process Languages
Spatial and Temporal Abstractions
Ontologies and Metadata
Scientific Discourse and Scientific Web Communities

Scientific Projects and Collaborations:

2009 ~ Editor of the SWAN interest group note Semantic Web for Health Care and Life Sciences Interest Group @ W3C
2008 ~ SWAN-SIOC Integration - Semantic Web for Health Care and Life Sciences Interest Group @ W3C
2008 - today ~ SCF Scientific Collaboration Framework @ Harvard Medical School
2006 - today ~ SWAN Semantic Web Applications in Neuromedicine @ Massachusetts General Hospital
2006 ~ ROL (Rete Oncologica Lombarda - Lombardia Oncological Network): evidence-based decision support focused on treatements compliance checking
2005 - today ~ Founder of the Java Data Processing Framework (JDPF, Tempo evolution)
2005 - 2007 ~ AMYLOIDOSIS PROJECT: Analysis, design and developement of an infrastructure for managing communication and patient data collection from a network of hospitals; an innovative electronic patient record with an unstructured database and archetypes/templates meta models defined through RDF; a decision support system for computerizing the clinical protocol.
2004 - 2007 ~ SIMILE PROJECT, Massachusetts Institute of Technology, MA, USA. SIMILE (Semantic Interoperability of Metadata and Information in unLike Environments): voluntary collaboration for the developement of the Welkin RDF browser.
2002 - 2005 ~ MIUR - FIRB: Le tecnologie dell'informazione e della comunicazione per la gestione dei processi di prevenzione, cura e riabilitazione. In qualità di responsabile della formalizzazione e automazione delle linee guida cliniche.
2002 - 2005 ~ Provincia autonoma di Trento - E-Heart Failure: A guideline-based shared care through a computer-based cooperative system for the management of heart failure. As responsible of the design and developement of the guieline based decision support system.
2002 - 2007 ~ THE GUIDE PROJECT, component-based multi-level architecture designed to integrate a formalized model of the medical knowledge contained in clinical guidelines and protocols with both workflow management systems and Electronic Patient Record technologies.

Random Conferences and Workshops:

2009 ~ 3rd Tinnitus Research Initiative Meeting, Stresa, Italy
2009 ~ Meeting on shared names for biomedical information records on the Web, Cambridge, MA, USA
2008 ~ Workshop on biomedical ontologies, Dallas TX, USA. - Signs, Symptoms and Findings: First Steps Toward an Ontology of Clinical Phenotypes
2006 ~ AMIA 2006, Washington DC, USA. - Talk: A Framework for Temporal Data Processing and Abstractions
2006 ~ Workshop Biomedical Ontology in Action, Baltimore, Maryland, USA.
2006 ~ Workshop for W3C Semantic Web Health Care & Life Sciences, Athens, GA, USA - Presentation of the SWAN project.
2006 ~ Workshop for the European project PIPS, Cambridge, UK - Invited talk: On Computerized Clinical Practice Guidelines.
2006 ~ I Workshop on Technologies for Healthcare & Healthy Lifestyle Proceedings, Valencia, Spain - Talk: Tempo a Framework for temporal data processing and abstractions.
2004 ~ Medinfo 2004, San Francisco, CA, USA - Talk: A Guideline Management System.
2004 ~ IDAMAP 2004, Stanford University, CA, USA - Talk: Genius: a new tool for gene networks visualization.
2004 ~ MIE 2004, Special Topic Conference: Contribution of Medical Informatics to Health. Munich, Germany.
2004 ~ EuroMise 2004, Prague, Checz Republic - Talk: A proposal for a method to improve the life cycle of a CPG implementation.
2003 ~ Workshop on Medical Ontologies. Rome, Italy.
2003 ~ MIE 2003, Special Topic Conference: Electronic Patient Records. Rome, Italy.
2003 ~ AIME 2003, Cyprus, Greece. Talk: The NewGuide Project: Guidelines, Information Sharing and Learning from Exceptions.
2002 ~ Advances in Clinical Knowledge Management 5, Cancer Research UK, London, United Kingdom. Talk: New-Guide: a new approach to representing clinical practice guidelines.
2001 ~ Methods for the Representation of Computer-Interpretable Clinical Guidelines, Cancer Research UK, London, United Kingdom.
2001 ~ Medinfo 2001, London, United Kingdom;

Latest talks:

2009, 25th June, Stresa, Italy
3rd Tinnitus Research Initiative Meeting
Tinnitusbook: a proposal for an advanced scientific web community for tinnitus research
2009, 23rd June, Brussels, Belgium
EU Workshop: Ontology-Driven Semantic Interoperability in eHealth
Semantics is not a luxury: Building the new generation of Clinical Information Systems
2009, 10th March, Cambridge, MA, USA
Cambridge Semantic Web Gatherings
SWAN Ontology 1.2
2008, 6th May, Portoroz, Slovenia
eHealth 2008, eHealth without frontiers
Medicognos knowledge and software solutions for continuity of care
2007, 26th May, Venice, Italy
Italian Society for Amyloidosis National Meeting
National Electronic Patient Record for Amyloidosis
2006, 12th November, Washington DC, USA
AMIA 2006
A Framework for Temporal Data Processing and Abstractions
2006, 20th June, Cambridge, UK
Invited talk for the Workshop for the EU project PIPS
The Guide Project

Research visits:

Massachusetts Institute of Technology (MIT), MIT Libraries, Cambridge, MA, USA
(October 2005)
Stanford University School of Medicine, Stanford Medical Informatics, CA, USA
(September 2004)

Scientific Publications:

2009 ~ Tinnitusbook: a proposal for an advanced scientific web community for tinnitus research
Attanasio Giuseppe, Ciccarese Paolo, Wu Elizabeth, Clark Tim, Pecis Emiliano.
Poster at 3rd Tinnitus Research Initiative Meeting
2008 ~ The SWAN biomedical discourse ontology
Paolo Ciccarese, Elizabeth Wu, Gwen Wong, Marco Ocana, June Kinoshita, Alan Ruttenberg, Tim Clark
J Biomed Inform. 2008 Oct;41(5):739-51. Epub 2008 May 4.
2007 ~ SWAN, a shared knowledge base for Alzheimer Disease research
June Kinoshita, Gwen Wong, Elizabeth Wu, Marco Ocana, Paolo Ciccarese, Tim Clark
Poster at Neuroscience 2007
2007 ~ E-learning for Occupational Medicine through an Interactive Guidelines Tool
Silvana Quaglini, Ezio Caffi, Paolo Ciccarese, Sergio Ghittori, Mazzoleni M.Cristina
Poster at MEDINFO 2007
2007 ~ An Extensible Software Framework for Temporal Data Processing
Cristiana Larizza, Paolo Ciccarese
Intelligent Data Analysis in Medicine and Pharmacology (IDAMAP) 2007 Proceedings
2007 ~ The Semantic Web Health Care and Life Sciences Interest Group work in progress: A large scale, OBO inspired, repository of biological knowledge based on Semantic Web technologies.
Matthias Samwald, William Bug, Jonathan Rees, Chris Mungall, John Barkley, Ray Hookway, Huajun Chen, Susie Stephens, Olivier Bodenreider, Kei-Hoi Cheung, Paolo Ciccarese, Tim Clark, Donald W Doherty, Kerstin Forsberg, Vipul Kashyap, June Kinoshita, Joanne Luciano, M Scott Marshall, Eric Neumann, Eric Prud'hommeaux, Daniel Rubin, Michael Travers, Gwen Wong, Elizabeth Wu, Alan Ruttenberg
Poster at Bio-Ontologies SIG Workshop 2007
2007 ~ An Overview of the SWAN 1.0 Discourse Ontology
Paolo Ciccarese, Elizabeth Wu, Tim Clark
WWW2007/HCLSDI Workshop
2006 ~ Developing SWAN, a shared knowledge base for Alzheimer's Disease research
Gwen. T. Wong, Yong Gao, Elizabeth Wu, Paolo Ciccarese, Marco Ocana, June Kinoshita, Tim Clark
Poster at Neuroscience 2006
2006 ~ A Framework for Temporal Data Processing and Abstractions
Paolo Ciccarese, Cristiana Larizza
Proceedings AMIA 2006
2006 ~ Models for guidelines representation
Silvana Quaglini, Paolo Ciccarese
Neurological Sciences, Springer, vol. 27 pag. S240-S244
2006 ~ Tempo: a Framework for temporal data processing and abstractions
Paolo Ciccarese, Cristiana Larizza
I Workshop on Technologies for Healthcare & Healthy Lifestyle
2005 ~ Architectures and Tools for innovative Health Information Systems: the Guide Project
Paolo Ciccarese, Ezio Caffi, Silvana Quaglini, Mario Stefanelli
International Journal of Medical Informatics ,ed Marius Fieschi, Mario Stefanelli and Casimir A. Kulikowski, vol. 74, pag. 553 - 562.
2004 ~ A Guideline Management System
Paolo Ciccarese, Ezio Caffi, Lorenzo Boiocchi, Silvana Quaglini, Mario Stefanelli.
Medinfo 2004 ,ed Fieschi/Coiera e Yu-Chan Jack Li, IOS Press ,pag. 28 - 32.
2004 ~ Genius: a new tool for gene networks visualization
Paolo Ciccarese, Stefano Mazzocchi, Fulvia Ferrazzi, Lucia Sacchi.
Intelligent Data Analysis in Medicine and Pharmacology (IDAMAP) Proceedings, ed Blaz Zupan, John H. Holmes , pag. 107 - 111.
2004 ~ Non-Compliance with Guidelines: Motivations and Consequences in a case study
Silvana Quaglini, Paolo Ciccarese, Giuseppe Micieli, Anna Cavallini.
Computer-based Support for Clinical Guidelines and Protocols, Proceedings CPG 2004 ,ed IOS Press , pag. 75 - 87.
2003 ~ Context-Based Task Ontologies for Clinical Guidelines
Kumar Anand, Ciccarese Paolo, Smith Barry, Piazza Matteo .
Pisanelli, Domenico M. (ed.): Ontologies in Medicine: Proceedings of the Workshop on Medical Ontologies ,ed IOS Press.
2003 ~ The NewGuide Project: guidelines, information sharing and Learning from Exceptions
Paolo Ciccarese, Ezio Caffi, Lorenzo Boiocchi, Assaf Halevy, Silvana Quaglini, Anand Kumar, Mario Stefanelli.
Artificial Intelligence in Medicine, Proceedings AIME 2003 ,ed Springer ,pag. 163 - 167.
2003 ~ Modular representation of the guideline text: An approach for maintainAing and updating the content of medical education
Anand Kumar, Silvana Quaglini, Mario Stefanelli, Paolo Ciccarese, Ezio Caffi.
Medical Informatics Internet Medicine. ,ed ,vol. 28 ,n. 2 ,pag. 99 - 115.
2003 ~ Relating UMLS semantic types and task-based ontology to computer-interpretable clinical practice guidelines
Anand Kumar, Paolo Ciccarese, Silvana Quaglini, Mario Stefanelli, Ezio Caffi, Lorenzo Boiocchi.
Proceedings of Medical Informatics Europe, St. Malo, France ,ed IOS Press ,pag. 469 - 474.
2003 ~ Comparing models of decision and action for guideline-based decision support: a case-study approach
M. Peleg, S. Tu, Paolo Ciccarese, A. Kumar, S. Quaglini, M. Stefanelli et al.
JAMIA ,ed American Medical Informatics Association ,vol. 10 ,n. 1 ,pag. 52 - 68.
2002 ~ A framework for representing and executing a clinical practice guideline for the management of high blood pressure in pregnancy
Anand Kumar, Silvana Quaglini, Mario Stefanelli, Paolo Ciccarese, Ezio Caffi, Lorenzo Boiocchi.
Technology and Health Care, vol. 10 ,pag. 517 - 519.
2002 ~ Modularized service-oriented guidelines in a distributed web-based environment : A data model and architecture for managing bioterrorism and its continuous surveillance
Anand Kumar, Silvana Quaglini, Mario Stefanelli, Paolo Ciccarese.
International Conference on emerging infectious diseases 2002, Programs and Abstracts Book.
2002 ~ New-Guide: a new approach to representing clinical practice guidelines
Paolo Ciccarese, Silvana Quaglini, Anand Kumar.
Proceedings of Advances in Clinical Knowledge Management 5.
2001 ~ New-Guide: Architecture
Paolo Ciccarese, Silvana Quaglini, Anand Kumar.
Proceedings of Open Clinical Workshop : Methods for the Representation of Clinical Guidelines.

Scientific Revision Activities:

IEEE Transactions on Information Technology in BioMedicine.
Briefings in Bioinformatics, Oxford University Press.
Artificial Intelligence in Medicine Europe.
Journal of Biomedical Informatics, Elsevier

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Paolo Ciccarese, PhD